Screen Thousands of Cell Co-Cultures in
One Standard Microplate
The TROVO benchtop instrument takes your existing workflow from 96 well plates to thousands of microwells.
- 3D print microwells
- Customize cell culture to mimic in vivo conditions
- Image for hours, days, or weeks
- AI-powered analysis of cellular kinetics
- Select and retrieve microcultures of interest in 5 minutes
Microculture Applications
-
Select T-cells with robust potency plus
meaningful proliferation - Identify and isolate rare cell types
- Accelerate cell line development
- Enrich cells for single-cell ‘omics analyses
Optimize T cell clone selection with Enrich TROVO. This platform uses hydrogel microwells and imaging to track T cell-tumor interactions, identifying top-performing clones for CAR-T and TCR-T development. TROVO’s efficient workflow isolates viable T cells for downstream analysis, expansion, and functional validation in just 12 days.
With very little human interaction, TROVO can bin microculture movies into several meaningful function-based groups. Highly promising T cell clones can easily and automatically be distinguished from undesirable clones. TROVO’s unique AI grouping of microculture movies eliminates user variability for cell selection and removes the need to stringently develop cell segmentation strategies, greatly increasing your lab’s efficiency.
TROVO is an “all in one” high throughput imaging system capable of monitoring individual B cell IgG secretion over time with the ability to recover cells of interest then. TROVO can print 20k of hydrogel-based microwells on a 6-well plate, allowing microenvironments to be established. B cells can easily be incubated in our microwells with antigen-coated beads or target cells (suspension/adherent) that can be labeled with a secondary antibody to detect secretion within just 2 hours. These sequestered cells can be tracked over time, captured, and recovered for expansion or sequencing.
Discover persistent tumor-killing T cells faster with Enrich TROVO. This microfluidics-free system preserves natural cell activity while enabling high-throughput coculture and real-time analysis of up to 36,000 T cell clones. In just three days, TROVO identifies top-performing clones, optimizing CAR-T, TCR-T, and TIL therapies with precision and efficiency.
Optimize live cell enrichment for single-cell RNA sequencing with Enrich TROVO. Using light-induced microgel lithography and image-based selection, TROVO gently isolates live cells from fresh or frozen tissue samples. Its fluidics-free design prevents clogging, preserves viability, and ensures higher transcriptomic integrity. Process up to three samples in four hours with results that maintain tissue-specific features and enable diverse cell detection in 10X Genomics analyses.
What’s a TROVO Demo Like?
Step 1
You grow 1-3 cell types prior
to our arrival
Step 2
We set TROVO up in your lab
(2 hours)
Step 3
You print microwells on the floor of a standard 6 well plate at the touch of a button (45 mins)
Step 4
You pipette your cells into the 6 wells and, if adherent, allow them to attach to the plate
Step 5
You load your plate into TROVO for imaging at multiple time points for up to 7 days
Step 6
Between imaging sessions, your plate lives in your incubator
Step 7
Using our advanced image analysis tools (or yours) you choose microwells with the best cell behavior
